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IWT-SBO: GlucoSens

Full Name: Enabling technologies for continuous glucose monitoring using implantable single-chip optical sensors

Duration: 1/11/2009-31/10/2013 (Finished)

Partners:

  • Ghent University – Photonics Research Group
  • Ghent University – Department of basic medical sciences: Tissue engineering group
  • Ghent University – Department of Surgery and Anesthesiology of domestic animals
  • Ghent University – Polymer Chemistry and Biomaterials Research Group
  • IMEC - INTEGSYS/HMS
  • KULeuven - Department Biosystems: Division of Mechatronics, Biostatistics and Sensors

Objective:

  • GlucoSens is a strategic basic research (SBO) project financed by the Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT), aimed at the development of enabling technologies for continuous glucose monitoring using implantable single-chip optical sensors.

INTEC's Role:

  • Development of single-chip spectrometer

Project Web site: http://www.glucosens.be

People involved

Research topics involved

Publications in the framework of this project (31)

    International Journals

  1. E.M.P. Ryckeboer, R. Bockstaele, M. Vanslembrouck, R. Baets, Glucose sensing by waveguide-based absorption spectroscopy on a silicon chip, Biomedical optics express, 5(5), p.1636–1648 doi:10.1364/boe.5.001636 (2014)  Download this Publication (5.5MB).
  2. E.M.P. Ryckeboer, J. Vierendeels, A. Lee, S. Werquin, P. Bienstman, R. Baets, Measurement of small molecule diffusion with an optofluidic silicon chip, Lab on a Chip, 13(22), p.4392 - 4399 doi:10.1039/C3LC50752A (2013)  Download this Publication (1.8MB).
  3. Y. De Koninck, F. Raineri, A. Bazin, R. Raj, G. Roelkens, R. Baets, Experimental demonstration of a hybrid III-V-on-silicon micro-laser based on resonant grating cavity mirrors, Optics Letters, 38(14), p.2496-2498 doi:10.1364/ol.38.002496 (2013)  Download this Publication (1018KB).
  4. Y. De Koninck, G. Roelkens, R. Baets, Design of a hybrid III-V-on-silicon microlaser with resonant cavity mirrors, IEEE Photonics Journal, 5(2), p.2700413 doi:10.1109/jphot.2013.2259586 (2013)  Download this Publication (901KB).
  5. E.M.P. Ryckeboer, A. Gassenq, M. Muneeb, N. Hattasan, S. Pathak, L. Cerutti, J-B Rodriguez, E. Tournie, W. Bogaerts, R. Baets, G. Roelkens, Silicon-on-insulator spectrometers with integrated GaInAsSb photodiodes for wide-band spectroscopy from 1510 to 2300 nm, Optics Express, doi:10.1364/oe.21.006101 (2013)  Download this Publication (2.1MB).
  6. N. Hattasan, B. Kuyken, F. Leo, E.M.P. Ryckeboer, D. Vermeulen, G. Roelkens, High-efficiency SOI fiber-to-chip grating couplers and low-loss waveguides for the short-wave infrared, IEEE Photonics Technology Letters, 24(17), p.1536-1538 doi:10.1109/lpt.2012.2208452 (2012)  Download this Publication (455KB).
  7. G. Roelkens, W. M. J, Green, B. Kuyken, X. Liu, N. Hattasan, A. Gassenq, L. Cerutti, J.B. Rodriguez, R. M. Osgood, E. Tournie, R. Baets, III-V/silicon photonics for short-wave infrared spectroscopy, Journal of quantum electronics (invited), doi:10.1109/jqe.2011.2178090 (2012)  Download this Publication (502KB).
  8. N. Hattasan, A. Gassenq, L. Cerutti, J. B. Rodriguez, E. Tournié, G. Roelkens, Heterogeneous integration of GaInAsSb p-i-n photodiodes on a silicon-on-insulator waveguide circuit , IEEE Photonics Technology Letters, 23(2011), p.1760 doi:10.1109/LPT.2011.2169244 (2011)  Download this Publication (425KB).
      International Conferences

    1. E.M.P. Ryckeboer, R. Bockstaele, R. Baets, Absorption spectroscopy of glucose based on a silicon photonics evanescent sensor, IEEE photonics conference 2013 (IPC), United States, p.paper TuA2.4 doi:10.1109/ipcon.2013.6656485 (2013)  Download this Publication (524KB).
    2. G. Roelkens, B. Kuyken, F. Leo, N. Hattasan, E.M.P. Ryckeboer, M. Muneeb, C. Hu, A. Malik, Z. Hens, R. Baets, Y. Shimura, F. Gencarelli, B. Vincent, R. Loo, P. Verheyen, G. Lepage , J. Van Campenhout, L. Cerutti, J.B. Rodriguez, E. Tournie, X. Chen, M. Nedeljkovic, G. Mashanovich, X. Liu, W. Green, Long-wavelength III-V/silicon photonic integrated circuits, Advanced Photonics - OSA Optics & Photonics Congress (invited), United States, p.paper IT2A.1 doi:10.1364/iprsn.2013.it2a.1 (2013)  Download this Publication (721KB).
    3. E.M.P. Ryckeboer, A. Gassenq, N. Hattasan, Cerutti, Laurent, Rodriguez, J.B., Tournie, Eric, R. Baets, G. Roelkens, Silicon-on-insulator spectrometers with integrated GaInAsSb photodiode array for wideband operation from 1500 to 2300 nm, CLEO, United States, p.paper JW2A.69.pdf doi:10.1364/cleo_at.2013.jw2a.69 (2013)  Download this Publication (340KB).
    4. R. Baets, A. Subramanian, A. Dhakal, S. Selvaraja, K. Komorowska, F. Peyskens, E.M.P. Ryckeboer, N.A Yebo, G. Roelkens, N. Le Thomas, Spectroscopy-on-chip applications of silicon photonics, Photonics West (invited), 8627(01), United States, p.86270I-1 - 86270I-10 doi:10.1117/12.2010498 (2013)  Download this Publication (1MB).
    5. N. Hattasan, A. Gassenq, L. Cerutti, J.B. Rodriguez, E. Tournié, G. Roelkens, GaSb-based integrated lasers and photodetectors on a Silicon-On-Insulator waveguide circuit for sensing applications in the shortwave infrared, Photonics Global Conference 2012, Singapore, doi:10.1109/pgc.2012.6458062 (2012)  Download this Publication (399KB).
    6. Y. De Koninck, F. Raineri, A. Bazin, R. Raj, G. Roelkens, R. Baets, Demonstration of a novel single-mode hybrid silicon microlaser, IEEE Photonics Conference, United States, doi:10.1109/ipcon.2012.6359320 (2012)  Download this Publication (839KB).
    7. Y. De Koninck, S. Keyvaninia, S. Stankovic, D. Van Thourhout, G. Roelkens, R. Baets, Hybrid silicon lasers for optical interconnect, IEEE Photonics Conference 2012 (invited), United States, p.812-813 doi:10.1109/ipcon.2012.6358871 (2012)  Download this Publication (271KB).
    8. N. Hattasan, A. Gassenq, L. Cerutti, J.B. Rodriguez, E. Tournié, G. Roelkens, InGaAsSb/GaSb lasers and photodetectors integrated on a Silicon-On-Insulator waveguide circuit for spectroscopic applications, International Workshop on Opportunities and Challenges in Mid-infrared Laser-based Gas Sensing (MIRSENS2), Poland, (2012)  Download this Publication (169KB).
    9. N. Hattasan, A. Gassenq, L. Cerutti, J.B. Rodriguez, E. Tournié, G. Roelkens, The study of integrated thin film GaSb-based Fabry Perot lasers: towards a fully integrated spectrometer on a Silicon-On-Insulator waveguide circuit, SPIE Photonics West, (2012)  Download this Publication (969KB).
    10. E.M.P. Ryckeboer, A. Gassenq, N. Hattasan, B. Kuyken, Cerutti Laurent, Rodriguez Jean-Baptiste, Tournie Eric, G. Roelkens, W. Bogaerts, R. Baets, Integrated spectrometer and integrated detectors on Silicon-on-Insulator for short-wave infrared applications, CLEO, United States, p.CTu1A.3 doi:10.1364/cleo_si.2012.ctu1a.3 (2012)  Download this Publication (284KB).
    11. E.M.P. Ryckeboer, W. Bogaerts, R. Baets, Silicon photonics based evanescent sensor for absorption spectroscopy of glucose, XI Conference on Optical Chemical Sensors and biosensors ( EUROPTRODE XI), Spain, p.37 (2012)  Download this Publication (196KB).
    12. K. Van Acoleyen, E.M.P. Ryckeboer, K. Komorowska, R. Baets, Light collection from scattering media in a silicon photonics integrated circuit, IEEE Photonics 2011 (IPC11), United States, p.543-544 doi:10.1109/pho.2011.6110662 (2011)  Download this Publication (587KB).
    13. N. Hattasan, A. Gassenq, B. Kuyken, L. Cerutti, J.B. Rodriguez, E. Tournie, D. Van Thourhout, G. Roelkens, Heterogeneously integrated InGaAsSb detectors on SOI waveguide circuits for short-wave infrared applications, Integrated Photonics Research, Silicon and Nano-Photonics (IPR), Canada, p.IWC5 doi:10.1364/iprsn.2011.iwc5 (2011)  Download this Publication (375KB).
    14. B. Kuyken, N. Hattasan, D. Vermeulen, S. Selvaraja, W. Bogaerts, W. M. J. Green, R. Baets, G. Roelkens, Highly efficient broadband silicon-on-insulator grating couplers for the short wave infrared wavelength range, Integrated Photonics Research, Silicon and Nano-Photonics (IPR), Canada, p.IMB6 doi:10.1364/iprsn.2011.imb6 (2011)  Download this Publication (673KB).
    15. N. Hattasan, L. Cerutti, J.B. Rodriguez, E. Tournie, D. Van Thourhout, G. Roelkens, Heterogeneous GaSb/SOI mid-infrared photonic integrated circuit for spectroscopic applications, SPIE Photonics West 2011 (invited), doi:10.1117/12.874659 (2011)  Download this Publication (2.2MB).
    16. E.M.P. Ryckeboer, N. Hattasan, G. Morren, D. Delbeke, W. Bogaerts, R. Baets, Power budget considerations for in vivo continuous glucose monitoring using absorption spectroscopy, Proceedings of the 2010 Annual Symposium of the IEEE Photonics Benelux Chapter, Netherlands, p.253-256 (2010)  Download this Publication (391KB).
    17. Y. De Koninck, G. Roelkens, R. Baets, Hybrid III-V/silicon micro-lasers based on resonant cavity reflectors, 15th Annual Meeting of the IEEE Photonics Society Benelux chapter, Netherlands, (2010)  Download this Publication (226KB).
    18. N. Hattasan, L. Cerutti, J.B. Rodriguez, E. Tournié, D. Van Thourhout, G. Roelkens, Heterogeneous integration of GaSb based photodetector on Silicon-on Insulator waveguide circuits for shortwave-infrared sensing applications, 15th Annual Symposium of the IEEE Photonics Benelux Chapter, (2010)  Download this Publication (310KB).
    19. G. Roelkens, N. Hattasan, E.M.P. Ryckeboer, D. Delbeke, D. Van Thourhout, R. Baets, Lab-on-a-chip approach based on heterogeneous III-V/silicon photonic integrated circuits for bio-medical applications, European Optical Society topical meeting on biophotonics, France, (2010)  Download this Publication (268KB).
    20. Y. De Koninck, G. Roelkens, R. Baets, Cavity Enhanced Reflector Based Hybrid Silicon Laser, 23rd Annual Meeting of the IEEE Photonics Society, United States, doi:10.1109/photonics.2010.5698964 (2010)  Download this Publication (534KB).
    21. G. Roelkens, N. Hattasan, E.M.P. Ryckeboer, D. Delbeke, D. Van Thourhout, R. Baets, Integrated III-V semiconductor/silicon photonic integrated circuits for bio-medical applications, Optics within Life Sciences, Canada, p.S7-p4 (2010)  Download this Publication (47KB).
    22. N. Hattasan, L. Cerutti, J.B. Rodriguez, E. Tournié, D. Van Thourhout, G. Roelkens, Heterogeneous Integration of GaSb-based epitaxy on silicon-on-insulator: towards mid-infrared photonic integrated circuits for environmental and bio-medical applications, 10th International Conference on Mid-Infrared Optoelectronics: Materials and Devices , China, p.90-91 (2010)  Download this Publication (157KB).
        National Conferences

      1. N. Hattasan, G. Roelkens, Can we measure gases from our mobile phone? Or knowing our glucose level in our body real time?, 11th UGent-FirW Phd Symposium, Belgium, (2012)  Download this Publication (137KB).